The systematic literature search was conducted by two independent examiners (VH, HP) using Covidence systematic review software (Veritas Health Innovation, Melbourne, Australia). The study protocol was prospectively registered in PROSPERO (CRD42020185294). The systematic literature search was conducted according to the PRISMA statement ( 5) and PICOS model (eTable 1) ( 6) in MEDLINE (PubMed), CINAHL, Scopus, EMBASE, CENTRAL from database inceptions until 05. The aim of the present review article was to develop evidence-based treatment recommendations for fractures of the base of MT5, based on a systematic search of the literature. Recommended treatment has therefore been a matter of debate ever since the times of Sir Robert. Moreover, the majority of those that do exist are not evidence-based. Consequently, there have been no consistent treatment recommendations to date ( 4). Unfortunately, the literature does not use uniform terminology here, with the result that the various studies report different treatment outcomes supposedly for the same fracture.
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